What is a Runeword? A combination of numerous runestones to create a buff on your gear is a Runeword. Check out our guide to learn more about how D2R Ladder Runes work! Items especially can be enhanced via the use of several Runewords to make your characters and their gear more powerful. How to create Runewords in Diablo 2 Resurrected While slaying the undead and demons of Sanctuary,...